|
KMID : 0984720060380050300
|
|
Infection and Chemotherapy
2006 Volume.38 No. 5 p.300 ~ p.303
|
|
|
A Case of Human Babesiosis Confirmed by Polymerase Chain Reaction and Treated with Atovaquone and Azithromycin
|
|
Youn Ki-Tae
Kim Yeon-A
Ku Nam-Su
Kim Jun-Hyung
Jung Se-Jin
Kim Hong-Jeoung
Song Kyung-Ho
Choi You-Kyoung
Shin So-Youn
Kim Young-Keun
Park Yoon-Sun
Choi Jun-Yong
Song Young-Goo
Kim June-Myung
|
|
|
Abstract
|
|
|
Human babesiosis is a tick-borne infectious disease caused by Babesia species. The clinical
diagnosis is difficult because of nonspecific symptoms like flu. Rapid diagnosis of human babesiosis
is microscopic examination in peripheral blood smear (Giemsa-stain) which reveals characteristic
forms of an intracellular quadruplet parasite. But differentiation between Babesia microti and
Plasmodium species can be quite difficult because of the morphologic similarity. We experienced a
case of human babesiosis. The patient was a 62-year old Korean male who had been in New Jersey,
U.S.A for 2 months. We initially diagnosed as malaria infection because the peripheral blood smear
revealed intracellular single ring form organism. But the patient was not improved significantly by the
treatment with chloroquine regimen. Finally we confirmed human babesiosis by polymerase chain
reaction for Babesia microti. We treated the patient successfully with a regimen of atovaquone and
azithromycin which has fewer adverse reactions than a regimen of clindamycin and quinine.
|
|
|
KEYWORD
|
|
|
Babesiosis, Babesia microti, Polymerase Chain Reaction, Atovaquone and Azithromycin
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|